- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Tanshinone IIA
Catalog No. | PI0138 |
---|---|
CAS No. | 568-72-9 |
Molecular Formula | C19H18O3 |
Molecular Weight | 294.34 |
Purity | 98% HPLC |
Package | 25 kg/drum |
Botanical Source | Salvia miltiorrhiza |
Appearance | Powder |
Shelf Life | 2 years |
Note: This tanshinone iia can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Tanshinone IIA
Handling of tanshinone iia should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Products
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Molecular Weight: 284.22
Purity: 98% HPLC
Package: 25 kg/drum
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Specification: 10%-30% Polyphenols UV
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Related Applications
Circulatory System Care
The circulatory system is an organ system that passes nutrients, gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases, stabilize body temperature and pH, and to maintain homeostasis. It's no secret that cardiovascular disease is the leading cause of death in all modern nations. Half of the population dies of heart attacks, strokes and other diseases related to the circulatory system. Many herbal extracts are beneficial to the circulatory system.
Related Researches
- 1. Activation of c-Jun N-terminal kinase mediates tanshinone IIA-induced apoptosis in KBM-5 chronic myeloid leukemia cells.
Yun SM, et al. Biol Pharm Bull 2013;36(2):208-14.
- 2. Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo.
Tao S, et al. Antioxid Redox Signal 2013 Mar 21.
- 3. Tanshinone IIA inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via Akt/Skp2/p27-associated pathway.
Luo Y, et al. PLoS One 2013;8(2):e56774.
- 4. IL-1β promotes corneal epithelial cell migration by increasing MMP-9 expression through NF-κB- and AP-1-dependent pathways.
Tseng HC, et al. PLoS One 2013;8(3):e57955.
- 5. Tanshinones Inhibit Amyloid Aggregation by Amyloid-β Peptide, Disaggregate Amyloid Fibrils, and Protect Cultured Cells.
Wang Q, et al. ACS Chem Neurosci 2013 Mar 29.
- 6. Akt mediates sodium tanshinone IIA silate inhibition of oxygen-glucose deprivation/reperfusion-induced myocardial cell apoptosis via suppression of the NF-κB/TNF-α pathway.
Wu WY, et al. Br J Pharmacol 2013 Mar 20.
- 7. Qualitative and quantitative analysis of the major constituents in Chinese medicinal preparation Dan-Lou tablet by ultra high performance liquid chromatography/diode-array detector/quadrupole time-of-flight tandem mass spectrometry.
Dong J, et al. J Pharm Biomed Anal 2013 Jun;80:50-62.
- 8. Impurities preparation of sodium tanshinone IIA sulfonate by high-speed counter-current chromatography and identification by liquid chromatography/multistage tandem mass spectrometry.
Chen S, et al. J Chromatogr A 2013 May 3;1288:28-34.
- 9. Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels.
Jin HJ, et al. Evid Based Complement Alternat Med 2013;2013:610694.
- 10. Tanshinone IIA reverses the malignant phenotype of SGC7901 gastric cancer cells.
Xu M, et al. Asian Pac J Cancer Prev 2013;14(1):173-7.