- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Sclareol
Catalog No. | PI0121 |
---|---|
CAS No. | 515-03-7 |
Molecular Formula | C20H36O2 |
Molecular Weight | 308.5 |
Purity | 97% HPLC |
Package | 25 kg/drum |
Botanical Source | clary sage (Salvia sclarea L.) |
Appearance | Off-white powderto amber colored solid |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This sclareol can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Sclareol
Handling of sclareol should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Applications
Flavorings and Fragrances
Natural flavors and fragrances are used almost ubiquitously in foods, beverages and cosmetics.For example, glycyrrhizic acid is a sweet compound containing potassium and calcium salts derived from licorice root. It is used as an expectorant and as a flavoring for pharmaceutics. Its sweetening effect is found to 1200 times that of sugar.
Related Researches
- 1. Bioactive constituents of Salvia chrysophylla Stapf.
Çulhao?lu B, et al. Nat Prod Res 2013 Mar;27(4-5):438-47.
- 2. Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions.
Russo A, et al. Food Chem Toxicol 2013 May;55:42-7.
- 3. Hh signaling inhibitors from Vitex negundo; naturally occurring inhibitors of the GLI1-DNA complex.
Arai MA, et al. Mol Biosyst 2013 Apr 2;9(5):1012-8.
- 4. Sclareol Reduces CD4+ CD25+ FoxP3+ Treg Cells in a Breast Cancer Model in Vivo.
Noori S, et al. Iran J Immunol 2013 Mar;10(1):10-21.
- 5. First enantiospecific synthesis of marine sesquiterpene quinol akaol A.
Alvarez-Manzaneda E, et al. Chem Commun (Camb) 2012 Jan 14;48(4):606-8.
- 6. Sclareol exhibits anti-inflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema model.
Huang GJ, et al. J Nat Prod 2012 Jan 27;75(1):54-9.
- 7. Identification of natural diterpenes that inhibit bacterial wilt disease in tobacco, tomato and Arabidopsis.
Seo S, et al. Plant Cell Physiol 2012 Aug;53(8):1432-44.
- 8. Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.
Caniard A, et al. BMC Plant Biol 2012 Jul 26;12:119.
- 9. Cancer cell spheroids as a model to evaluate chemotherapy protocols.
Perche F, et al. Cancer Biol Ther 2012 Oct;13(12):1205-13.
- 10. A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate.
Günnewich N, et al. Phytochemistry 2012 Sep 5.