- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Osthole
Catalog No. | PI0103 |
---|---|
CAS No. | 484-12-8 |
Molecular Formula | C15H16O3 |
Molecular Weight | 244.29 |
Purity | 30%, 50%, 95% HPLC |
Package | 25 kg/drum |
Botanical Source | Cnidium monnieri (L.) Cuss |
Appearance | Green-yellow powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Note: This osthole can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. |
Safety Tips of Osthole
Handling of osthole should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
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Related Applications
Liver Protection
The liver is the primary organ responsible for expelling and breaking down toxins entering the body. In particular, it produces bile, a detoxifying agent metabolically indispensable in breaking down fats from food. Many chemicals from nature could protect liver to help the process of detoxication.Men's Health Care
More and more men are plagued by the disease of erectile dysfunction. Erectile dysfunction is a frustrating sexual dysfunction which affects close to 18 million men in the U.S. This dysfunction is recognized by the inability to create or maintain an erection during sexual intercourse. Many chemicals from nature could be benefit men in this regard, such as yohimbine and saw palmetto extract.
Related Researches
- 1. Comparative study of pharmacokinetics and tissue distribution of osthole in rats after oral administration of pure osthole and Libanotis buchtormensis supercritical extract.
Shi J, et al. J Ethnopharmacol 2013 Jan 9;145(1):25-31.
- 2. Osthole relaxes pulmonary arteries through endothelial phosphatidylinositol 3-kinase/Akt-eNOS-NO signaling pathway in rats.
Yao L, et al. Eur J Pharmacol 2013 Jan 15;699(1-3):23-32.
- 3. Investigation of the biotransformation of osthole by liquid chromatography/tandem mass spectrometry.
Li J, et al. J Pharm Biomed Anal 2013 Feb 23;74:156-61.
- 4. Coumarins from the Herb Cnidium monnieri and Chemically Modified Derivatives as Antifoulants against Balanus albicostatus and Bugula neritina Larvae.
Wang ZC, et al. Int J Mol Sci 2013 Jan 9;14(1):1197-206.
- 5. Osthole protects lipopolysaccharide-induced acute lung injury in mice by preventing down-regulation of angiotensin-converting enzyme 2.
Shi Y, et al. Eur J Pharm Sci 2013 Mar 12;48(4-5):819-24.
- 6. A rapid and sensitive LC-MS/MS method for the determination of osthole in rat plasma: application to pharmacokinetic study.
Yun F, et al. Biomed Chromatogr 2013 May;27(5):676-80.
- 7. Simultaneous determination of scopoletin, psoralen, bergapten, xanthotoxin, columbianetin acetate, imperatorin, osthole and isoimperatorin in rat plasma by LC-MS/MS for pharmacokinetic studies following oral administration of Radix Angelicae Pubescentis e
Chang YX, et al. J Pharm Biomed Anal 2013 Apr 15;77:71-5.
- 8. Osthole ameliorates renal ischemia-reperfusion injury in rats.
Zheng Y, et al. J Surg Res 2013 Feb 1.
- 9. Combined anticancer activity of osthole and cisplatin in NCI-H460 lung cancer cells in vitro.
Xu XM, et al. Exp Ther Med 2013 Mar;5(3):707-710.
- 10. Osthole Improves Spatial Memory Deficits in Rats via Hippocampal α 1-Adrenergic and D 1 /D 2 Receptors.
Lin LW, et al. Evid Based Complement Alternat Med 2013;2013:273682.