- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Diosmetin
| Catalog No. | PI0050 |
|---|---|
| CAS No. | 520-34-3 |
| Molecular Formula | C16H12O6 |
| Molecular Weight | 300.26 |
| Purity | 98% HPLC |
| Package | 25 kg/drum |
| Botanical Source | Citrus limon (L.) Burm |
| Appearance | Yellow powder |
| Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
| Shelf Life | 2 years |
| Note: This diosmetin can also be used as reference standards. You can find it under the category of Reference Substance at Herbalext.com. | |
Safety Tips of Diosmetin
Handling of diosmetin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Applications
Antioxidant Supplements
Antioxidants are one kind of molecules, helping to neutralize harmful free radicals which can accelerate cellular oxidation. They provide an important and solid defense against the diseases caused by oxidative stress, such as cancer, heart disease, decline in brain function, immune system and aging. Because antioxidants are capable of stabilizing or deactivating the free radicals from oxidation reactions before they attack cells.
Related Researches
- 1. The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation.
Androutsopoulos VP, et al. J Nutr Biochem 2013 Feb;24(2):496-504.
- 2. Bioactivity of Diosmetin Glycosides Isolated from the Epicarp of Date Fruits, Phoenix dactylifera, on the Biochemical Profile of Alloxan Diabetic Male Rats.
Michael HN, et al. Phytother Res 2013 May;27(5):699-704.
- 3. HPLC-PDA-MS and NMR characterization of a hydroalcoholic extract of Citrus aurantium L. var. amara peel with antiedematogenic activity.
Mencherini T, et al. J Agric Food Chem 2013 Feb 27;61(8):1686-93.
- 4. Novel macrocyclic monoterpene glycosides from bioactive extract of Parkinsonia aculeata L.
Marzouk MS, et al. Cell Biochem Biophys 2013 Apr;65(3):301-13.
- 5. Simultaneous quantification and validation of caffeoylquinic acids and flavonoids in Hemistepta lyrata and peroxynitrite-scavenging activity.
Nugroho A, et al. J Pharm Biomed Anal 2013 Mar 25;76:139-44.
- 6. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase.
Chan BC, et al. Phytomedicine 2013 May 15;20(7):611-4.
- 7. Alkyl and phenolic glycosides from Saussurea stella.
Wang TM, et al. Fitoterapia 2013 Apr 6.
- 8. Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction.
Hu CQ, et al. J Asian Nat Prod Res 2012;14(4):370-81.
- 9. A new flavonol glycoside from Hylomecon vernalis.
Lee SY, et al. Arch Pharm Res 2012 Mar;35(3):415-21.
- 10. Simultaneous qualitative assessment and quantitative analysis of flavonoids in various tissues of lotus (Nelumbo nucifera) using high performance liquid chromatography coupled with triple quad mass spectrometry.
Chen S, et al. Anal Chim Acta 2012 Apr 29;724:127-35.
