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- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Norcantharidin
Catalog No. | PI0096 |
---|---|
CAS No. | 5442-12-6 |
Molecular Formula | C8H8O4 |
Molecular Weight | 168.15 |
Purity | 98% HPLC |
Package | 100g; 500g; 1 kg |
Appearance | Powder |
Shelf Life | 2 years |
Safety Tips of Norcantharidin
Handling of norcantharidin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
Related Products
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CAS No.: 520-36-5
Molecular Weight: 270.25
Purity: 98% HPLC
Package: 25 kg/drum
Related Applications
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Each year, more and more people are getting cancer, especially lung and liver cancer. However, there are not enough good anti-cancer drugs. Fortunately, many herbal extracts have good antineoplastic activity. A plant-based diet can help shield you from cancer because plants are rich in anti-inflammatory and antioxidant substances that help us withstand exposure to ultraviolet radiation, air pollution and other noxious substances.
Related Researches
- 1. Norcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells in vitro and in nude mouse xenografts.
Du HF, et al. Leuk Lymphoma 2013 Mar;54(3):607-18.
- 2. Clinical report on transarterial neoadjuvant chemotherapy of malignant fibrous histiocytoma in soft tissue.
Guo J, et al. Clin Transl Oncol 2013 May;15(5):370-5.
- 3. Norcantharidin suppresses cell growth and migration with enhanced anticancer activity of gefitinib and cisplatin in human non-small cell lung cancer cells.
Lee YC, et al. Oncol Rep 2013 Jan;29(1):237-43.
- 4. Cantharidin as an antitumor agent: a retrospective review.
Deng LP, et al. Curr Med Chem 2013;20(2):159-66.
- 5. Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways.
Zhang L, et al. Cancer Sci 2013 May;104(5):604-10.
- 6. Exploiting Protein Phosphatase Inhibitors Based on Cantharidin Analogues for Cancer Drug Discovery.
Deng L, et al. Mini Rev Med Chem 2013 Jan 31.
- 7. Effect of alginate-chitosan sustained release microcapsules for transhepatic arterial embolization in VX2 rabbit liver cancer model.
Zhang GY, et al. J Biomed Mater Res A 2013 Apr 2.
- 8. Norcantharidin inhibits DNA replication and induces mitotic catastrophe by degrading initiation protein Cdc6.
Chen S, et al. Int J Mol Med 2013 Apr 23.
- 9. Novel norcantharidin-loaded liver targeting chitosan nanoparticles to enhance intestinal absorption.
Bei YY, et al. Int J Nanomedicine 2012;7:1819-27.
- 10. Norcantharidin triggers cell death and DNA damage through S-phase arrest and ROS-modulated apoptotic pathways in TSGH 8301 human urinary bladder carcinoma cells.
Yu CC, et al. Int J Oncol 2012 Sep;41(3):1050-60.