- API
Any substance that is represented for use in a drug and that, when used in the manufacturing, processing, or packaging ...
- Active Ingredient
Any component that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, ...
- CAS No.
Unique number assigned to a specific chemical (identified by its chemical name) by the American Chemical Society and ...
Milk Thistle Extract
Catalog No. | HE0150 |
---|---|
Purity | 80% Silymarin UV/HPLC 30%-40% Silybin HPLC; 20%-45% UV water soluble |
Package | 25 kg/drum |
Botanical Source | Milk Thistle |
Appearance | Powder |
Storage | Stored in cool and dry places, protected from direct sunlight and heat. |
Shelf Life | 2 years |
Safety Tips of Milk Thistle Extract
Handling of milk thistle extract should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.
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Related Applications
Antioxidant Supplements
Antioxidants are one kind of molecules, helping to neutralize harmful free radicals which can accelerate cellular oxidation. They provide an important and solid defense against the diseases caused by oxidative stress, such as cancer, heart disease, decline in brain function, immune system and aging. Because antioxidants are capable of stabilizing or deactivating the free radicals from oxidation reactions before they attack cells.
Related Researches
- 1. Evaluation of the effect of hydroxypropyl-β-cyclodextrin on topical administration of milk thistle extract.
Spada G, et al. Carbohydr Polym 2013 Jan 30;92(1):40-7.
- 2. Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis.
El-Lakkany NM, et al. Parasit Vectors 2012 Jan 11;5:9.
- 3. Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling.
Deep G, et al. PLoS One 2012;7(4):e34630.
- 4. A sensitive LC-MS/MS assay for the simultaneous analysis of the major active components of silymarin in human plasma.
Brinda BJ, et al. J Chromatogr B Analyt Technol Biomed Life Sci 2012 Aug 1;902:1-9.
- 5. Chemotherapeutic activity of silymarin combined with doxorubicin or paclitaxel in sensitive and multidrug-resistant colon cancer cells.
Colombo V, et al. Cancer Chemother Pharmacol 2011 Feb;67(2):369-79.
- 6. Oral bioavailability of silymarin phytocomplex formulated as self-emulsifying pellets.
Iosio T, et al. Phytomedicine 2011 Apr 15;18(6):505-12.
- 7. Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle.
Dunnick JK, et al. Toxicol Pathol 2011 Feb;39(2):398-409.
- 8. Toxicology and carcinogenesis studies of milk thistle extract (CAS No. 84604-20-6) in F344/N rats and B6C3F1 mice (Feed Studies).
National Toxicology Program. Natl Toxicol Program Tech Rep Ser 2011 May;(565):1-177. Review.
- 9. Identification of hepatoprotective flavonolignans from silymarin.
Polyak SJ, et al. Proc Natl Acad Sci U S A 2010 Mar 30;107(13):5995-9.
- 10. Silibinin reverses epithelial-to-mesenchymal transition in metastatic prostate cancer cells by targeting transcription factors.
Wu K, et al. Oncol Rep 2010 Jun;23(6):1545-52.